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Biomarkers
Biomarkers
41 biomarkers decide at least one EU-approved indication, grouped here by how they are usually tested. Each page lists the drugs and cut-offs by tumour type. The number is the count of approved indications.
Immunohistochemistry
PD-L1
37
HER2
33
Hormone receptor
26
CD30
5
CD20
3
KIT
2
CLDN18.2
1
EpCAM
1
FRα
1
IHC or molecular
ALK
25
MMR/MSI
14
ROS1
5
NTRK
3
Molecular
EGFR
34
BCR::ABL1
27
BRAF
26
BRCA1/2
9
FLT3
7
RAS
6
RET
6
IDH1/2
4
PML::RARA
4
ESR1
3
FGFR
3
PDGFR
3
PIK3CA
3
TP53/del(17p)
3
del(5q)
2
KRAS
2
MET
2
AKT1/PIK3CA/PTEN
1
EBV
1
FIP1L1::PDGFRA
1
HRD
1
Other tests
CD19
6
CD22
2
AFP
1
CD33
1
HLA-A*02:01
1
PSMA
1
Somatostatin receptor
1
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